CD33 antibody

Catalog No. ABIN2689195

Product Details anti-CD33 Antibody

Target: CD33

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD33 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Brand: BD Pharmingen™

Characteristics: Reacts with a 67 kDa type I transmembrane glycoprotein expressed on monocytes, activated T cells, myeloid progenitors as well as mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes and hematopoietic stem cells. Reports indicate that this glycoprotein can function as a sialic acid-dependent cell adhesion molecule. This function can be modulated by endogenous sialoglycoconjugates when CD33 is expressed on the membrane. HIM3-4 reacts with human and monkey granulocytes and monocytes. Profile of peripheral bllood monocytes analyzed on a FACScan (BDIS San Jose, CA).

BD Pharmingen™ Purified Mouse Anti-Human CD33 - Purified - Clone HIM3-4 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: HIM3

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD33 antibody (ABIN2689195)

Freeman, Kelm, Barber, Crocker: "Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules." in: Blood, Vol. 85, Issue 8, pp. 2005-12, (1995) (PubMed).

Nakamura, Noma, Kidokoro, Kobayashi, Takei, Kurashima, Mukaiyama, Kato: "Expression of CD33 antigen on normal human activated T lymphocytes." in: Blood, Vol. 83, Issue 5, pp. 1442-3, (1994) (PubMed).

Favaloro, Moraitis, Koutts, Exner, Bradstock: "Endothelial cells and normal circulating haemopoietic cells share a number of surface antigens." in: Thrombosis and haemostasis, Vol. 61, Issue 2, pp. 217-24, (1989) (PubMed).

Target Details for CD33

Target: CD33

Alternative Name: CD33 (CD33 Products)

Synonyms: SIGLEC-3 antibody, SIGLEC3 antibody, p67 antibody, Siglec-3 antibody, gp67 antibody, CD33 molecule antibody, CD33 antigen antibody, CD33 antibody, Cd33 antibody