CD79a antibody
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- Target See all CD79a (CD79A) Antibodies
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD79a antibody is un-conjugated
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Application
- Intracellular Staining (ICS)
- Brand
- BD Pharmingen™
- Characteristics
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Reacts with the cytoplasmic domain of a 47 kDa membrane glycoprotein present on B lymphocytes, also referred to as mb-1. It is expressed on B cells at various stages of differentiation, from pre-B cell stage, probably before expression of cytoplasmic μ chain, to plasma cell stage, in which it is detected only in the cytoplasm. CD79a associates with CD79b to form part of the B-cell receptor complex. It has been suggested that CD79a may play a role in mediating the transport of IgM to the cell surface. This antibody has been found to react on permeabilized A20 cells (mouse B cell line). Profile of permeabilized peripheral blood lymphocytes with Cytofix/Cytoperm (Cat# 554714) analyzed on a FACScan
BD Pharmingen™ Purified Mouse Anti-Human CD79a - Purified - Clone HM47 - Isotype Mouse IgG1, κ - Reactivity Hu, Ms - 0.1 mg - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Clone
- HM47
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD79A Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C.
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The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 11, pp. 2474-82, (1991) (PubMed).
: "B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties." in: The EMBO journal, Vol. 7, Issue 11, pp. 3457-64, (1989) (PubMed).
: "
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The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 11, pp. 2474-82, (1991) (PubMed).
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- Target
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- Alternative Name
- CD79a (CD79A Products)
- Synonyms
- CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody
- Background
- Synonyms: Igα, mb-1
- Pathways
- BCR Signaling
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