CD11b antibody

Catalog No. ABIN2704154

This anti-CD11b antibody is a Mouse Monoclonal antibody detecting CD11b in FACS. Suitable for Human.

Quick Overview for CD11b antibody (ABIN2704154)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD11b antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: OKM1

Product Details anti-CD11b Antibody

Purpose: CD11b Unconjugated Antibody

Characteristics: The clone OKM1, a mouse monoclonal antibody, binds with a 165 kDa adhesion glycoprotein present in human cells known as CD11b. CD11b associates with the 95 kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3).

Purification: Purified

Purity: >95 %

Immunogen: Human PBMC

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: CD11b

NCBI Accession: NM_000632

UniProt: P11215

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation