Retinoblastoma 1 antibody (pSer780)

Catalog No. ABIN7296800

The Rabbit Polyclonal anti-Retinoblastoma 1 antibody (ABIN7296800) specifically detects Retinoblastoma 1 in WB, IHC and IF. The antibody is reactive with Human, Mouse, Rat, Cow, Dog and Pig samples.

Quick Overview for Retinoblastoma 1 antibody (pSer780) (ABIN7296800)

Target: Retinoblastoma 1 (RB1)

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Retinoblastoma 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Retinoblastoma 1 Antibody

Binding Specificity: pSer780

Purpose: Rabbit polyclonal antibody to RB1 (Phospho-S780)

Specificity: Recognizes endogenous levels of RB1 protein only when phosphorylated at S780.

Characteristics: Rabbit polyclonal antibody to RB1 (pS780)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S780 of human RB1 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Retinoblastoma 1

Target: Retinoblastoma 1 (RB1)

Alternative Name: RB1

Background: Retinoblastoma-associated protein, p105-Rb, pRb, Rb, pp110

Gene ID: 5925, 19645, 24708

UniProt: P06400

Pathways: Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy