BAX antibody (Center)

Catalog No. ABIN7295000

There is 1 publication for this product available. The Rabbit Polyclonal anti-BAX antibody is suitable to detect BAX in samples from Human, Mouse, Rat, Pig and Cow. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for BAX antibody (Center) (ABIN7295000)

Target: BAX (BCL2-Associated X Protein (BAX))

Reactivity: Human, Mouse, Rat, Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-BAX Antibody

Binding Specificity: Center

Purpose: Rabbit polyclonal antibody to BAX

Specificity: Recognizes endogenous levels of BAX protein.

Characteristics: Rabbit polyclonal antibody to BAX

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BAX. The exact sequence is proprietary.

Application Details

Application Notes: E (1/5000 - 1/10000), WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

References for anti-BAX antibody (ABIN7295000)

Xu, Wang, Banan, Chirumbole, Garcia-Aroz, Balakrishnan, Nayak, Zhang, Jia, Upadhya, Gaut, Hiebsch, Manning, Wu, Lin, Chapman: "Anti-CD47 monoclonal antibody therapy reduces ischemia-reperfusion injury of renal allografts in a porcine model of donation after cardiac death." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 18, Issue 4, pp. 855-867, (2018) (PubMed).

Target Details for BAX

Target: BAX (BCL2-Associated X Protein (BAX))

Alternative Name: BAX

Background: BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4

Gene ID: 581, 12028

UniProt: Q07812

Pathways: p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response