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RASSF1 antibody

RASSF1 Reactivity: Human WB, IF, IHC, FACS Host: Mouse Monoclonal 2B11 unconjugated
Catalog No. ABIN2730552
  • Target See all RASSF1 Antibodies
    RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
    Reactivity
    • 54
    • 27
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 10
    • 1
    Mouse
    Clonality
    • 46
    • 9
    Monoclonal
    Conjugate
    • 26
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RASSF1 antibody is un-conjugated
    Application
    • 27
    • 21
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Characteristics
    Homo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A
    Purification
    Purified from mouse ascites fluids by affinity chromatography
    Immunogen
    Full length human recombinant protein of human RASSF1 (NP_009113) produced in E.coli.
    Clone
    2B11
    Isotype
    IgG1
    Top Product
    Discover our top product RASSF1 Primary Antibody
  • Application Notes
    WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
    Comment

    The concentration of the product may vary between diferrent lots.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
    Alternative Name
    RASSF1 (RASSF1 Products)
    Background
    This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
    Molecular Weight
    38.6 kDa
    Gene ID
    11186
    NCBI Accession
    NM_007182
    HGNC
    28844
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