Estrogen Receptor alpha antibody (AA 2-185)

Catalog No. ABIN2740746

The Mouse Monoclonal anti-Estrogen Receptor alpha antibody is suitable to detect Estrogen Receptor alpha in samples from Human. It has been validated for IF and FACS.

Quick Overview for Estrogen Receptor alpha antibody (AA 2-185) (ABIN2740746)

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Estrogen Receptor alpha antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: ER506

Product Details anti-Estrogen Receptor alpha Antibody

Binding Specificity: AA 2-185

Specificity: Human Estrogen Receptor

Purification: Protein G purified

Immunogen: Recombinant human Estrogen Receptor alpha protein (aa2-185).

Type of Immunogen: Recombinant protein

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: Flo, IF (1:50 - 1:100)

Usage: This antibody is specific to estrogen receptor (ER) alpha and shows minimal cross-reaction with other members of the family. Estrogen receptor (ER) is an important regulator of growth and differentiation in the mammary gland. Presence of estrogen receptor (ER) in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for Estrogen Receptor alpha

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Alternative Name: Estrogen Receptor

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly