S1PR1 antibody (C-Term)
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- Target See all S1PR1 Antibodies
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This S1PR1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- Human S1PR1 / EDG1 / S1P1.
- Purification
- Protein A purified
- Immunogen
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A recombinant protein fragment from the C-terminal portion of human EDG1.
Type of Immunogen: Recombinant protein - Isotype
- IgG
- Top Product
- Discover our top product S1PR1 Primary Antibody
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- Application Notes
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Approved: WB (4 - 6 μg/mL)
Usage: EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P). Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- avoid freeze thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
- Alternative Name
- S1PR1 / EDG1 / S1P1 (S1PR1 Products)
- Synonyms
- CD363 antibody, CHEDG1 antibody, D1S3362 antibody, ECGF1 antibody, EDG-1 antibody, EDG1 antibody, S1P1 antibody, AI849002 antibody, Edg1 antibody, Lpb1 antibody, S1p antibody, S1p1 antibody, S1P receptor 1 antibody, S1P receptor Edg-1 antibody, edg1 antibody, etID43307.22 antibody, s1p1 antibody, wu:fb98f05 antibody, s1pr1 antibody, xts1p1 antibody, sphingosine-1-phosphate receptor 1 antibody, sphingosine-1-phosphate receptor 1 L homeolog antibody, S1PR1 antibody, S1pr1 antibody, s1pr1 antibody, s1pr1.L antibody
- Background
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Name/Gene ID: S1PR1
Subfamily: Lysophospholipid/Lysosphingolipid
Family: GPCR
Synonyms: S1PR1, CD363, CD363 antigen, CHEDG1, ECGF1, EDG-1, D1S3362, EDG1, S1P1, S1P receptor Edg-1, S1P receptor 1 - Gene ID
- 1901
- Pathways
- Signaling Events mediated by VEGFR1 and VEGFR2
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