TAG-72 antibody
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- Target See all TAG-72 Antibodies
- TAG-72 (Temporarily Assigned Gene Name Family Member (TAG-72))
- Reactivity
- Human, Rat, Cow, Dog, Hamster
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TAG-72 antibody is un-conjugated
- Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), ELISA
- Specificity
- Human TAG-72
- Purification
- Protein G purified
- Immunogen
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The membrane-enriched fraction of a human breast carcinoma liver metastasis.
Type of Immunogen: Membrane preparation - Clone
- B72-3
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TAG-72 Primary Antibody
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- Application Notes
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Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)
Usage: This antibody recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 Ab with a GCDFP-15 Ab is valuable in the diagnosis of apocrine carcinoma. ELISA: Order BSA-free format for coating. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2°C to 8°C.
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- Target
- TAG-72 (Temporarily Assigned Gene Name Family Member (TAG-72))
- Alternative Name
- TAG-72 (TAG-72 Products)
- Synonyms
- mRNA cap guanine-N7 methyltransferase antibody, tag-72 antibody
- Background
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Name/Gene ID: TAG-72
Synonyms: TAG-72
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