TGFA antibody (C-Term)

Catalog No. ABIN2744783

Product Details anti-TGFA Antibody

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This TGFA antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Rat TGFA / TGF Alpha

Purification: Protein G purified

Immunogen: A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGF alpha.

Type of Immunogen: Synthetic peptide

Clone: MF9

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: Flo (0.5 - 1 μg/10 x10⁶), IF (1 - 2 μg/mL), IHC, IHC-P (1 - 2 μg/mL), WB (0.5 - 1 μg/mL)

Usage: TGF alpha is a growth factor with 33 % homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype. This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. Staining with the antibody is completely blocked by the peptide used for raising this antibody. ELISA: Order BSA-free format for coating.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C to 8°C.

Target Details for TGFA

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Alternative Name: TGFA / TGF alpha (TGFA Products)

Synonyms: TFGA antibody, LOC100009482 antibody, TGF alpha antibody, TGFA antibody, wa-1 antibody, wa1 antibody, RATTGFAA antibody, TGFAA antibody, NV15606 antibody, si:ch211-10e8.7 antibody, transforming growth factor alpha antibody, transforming growth factor alpha L homeolog antibody, transforming growth factor-alpha antibody, transforming growth factor, alpha antibody, TGFA antibody, TGF-A antibody, Tgfa antibody, tgfa.L antibody, LOC100121300 antibody, LOC100009150 antibody, tgfa antibody

Background: Name/Gene ID: TGFA
Family: TGF beta

Synonyms: TGFA, Etgf, TFGA, TGF Alpha, Tgf type 1, TGF-alpha, Egf-like tgf

Gene ID: 7039

Pathways: NF-kappaB Signaling, RTK Signaling, EGFR Signaling Pathway