PDE3B antibody (AA 1050-2000)

Catalog No. ABIN2747092

Product Details anti-PDE3B Antibody

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Binding Specificity: AA 1050-2000

Reactivity: Human, Mouse, Rat, Chicken, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE3B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Confocal Microscopy (CM)

Purification: Affinity Purified

Immunogen: Synthetic peptide taken within amino acid region 1050-2000 on mouse PDE3B protein. Will label all variants of PDE3B.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 μg/μL

References for anti-PDE3B antibody (ABIN2747092)

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Dov, Abramovitch, Warwar, Nesher: "Diminished phosphodiesterase-8B potentiates biphasic insulin response to glucose." in: Endocrinology, Vol. 149, Issue 2, pp. 741-8, (2008) (PubMed).

Netherton, Maurice: "Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis." in: Molecular pharmacology, Vol. 67, Issue 1, pp. 263-72, (2005) (PubMed).

Target Details for PDE3B

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Alternative Name: PDE3B (PDE3B Products)

UniProt: Q63085

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process