HIP1 antibody (AA 410-690)

Catalog No. ABIN2753733

Product Details anti-HIP1 Antibody

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Binding Specificity: AA 410-690

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity purified

Immunogen: Recombinant Human Huntingtin-interacting protein 1 protein (410-690AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HIP1

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Alternative Name: HIP1 (HIP1 Products)

Synonyms: HIP-I antibody, ILWEQ antibody, CG10971 antibody, Dmel\\CG10971 antibody, Hip1R antibody, 2610109B09Rik antibody, A930014B11Rik antibody, E130315I21Rik antibody, mKIAA4113 antibody, huntingtin interacting protein 1 antibody, Huntingtin interacting protein 1 antibody, HIP1 antibody, Hip1 antibody, hip1 antibody

Background:

Background: Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors.

Aliases: 2610109B09Rik antibody, A930014B11Rik antibody, E130315I21Rik antibody, HIP 1 antibody, HIP I antibody, HIP-1 antibody, HIP-I antibody, hip1 antibody, HIP1/PDGFRB fusion gene antibody, HIP1/PDGFRB fusion gene, included antibody, HIP1_HUMAN antibody, HIPI antibody, Huntingtin interacting protein 1 antibody, Huntingtin Interacting Protein HIP1 antibody, Huntingtin-interacting protein 1 antibody, Huntingtin-interacting protein I antibody, ILWEQ antibody, KIAA4113 antibody, MGC126506 antibody, MGC27616 antibody, mKIAA4113 antibody

UniProt: O00291

Pathways: Positive Regulation of Endopeptidase Activity