SGPL1 antibody

Catalog No. ABIN2764172

Product Details anti-SGPL1 Antibody

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPL1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Cow, Human, Mouse, Rat

Characteristics: EC 4.1.2.27, SP-lyase, hSPL or Sphingosine-1-phosphate aldolase. Gene name: SGPL1 or KIAA1252,Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. The catalytic activity of sphingosine 1-phosphate lyase converts sphingosine 1-phosphate to phosphoethanolamine and palmitaldehyde using Pyridoxal phosphate as a co-factor. Sphingosine 1-phosphate lyase is a type III membrane protein found in the endoplasmic reticulum. Sphingosine 1-phosphate lyase is found primarily in the liver and kidney. Sphingosine 1-phosphate lyase belongs to the group II decarboxylase family.

Purification: Antigen Immunoaffiinity Purification

Immunogen: Synthetic peptide derived from the sphingosine 1-phosphate lyase 1 protein.

Isotype: IgG

Application Details

Application Notes: Antibody can be used for Western blotting (1:400 dilution). Other applications not yet tested. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Provided as ligand affinity purified antibody in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for SGPL1

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Alternative Name: Sphingosine 1-Phosphate Lyase 1 (SGPL1 Products)

Synonyms: SGPL1 antibody, zgc:162153 antibody, AI428538 antibody, D10Xrf456 antibody, S1PL antibody, Spl antibody, SPL antibody, Spgl1 antibody, spl antibody, sphingosine-1-phosphate lyase 1 antibody, sphingosine-1-phosphate lyase 1 L homeolog antibody, sphingosine phosphate lyase 1 antibody, SGPL1 antibody, sgpl1.L antibody, sgpl1 antibody, Sgpl1 antibody

UniProt: O95470

Pathways: Platelet-derived growth Factor Receptor Signaling