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RNF216 antibody (N-Term)
RNF216
Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RNF216 Antibody
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Target
See all RNF216 Antibodies
RNF216
(Ring Finger Protein 216 (RNF216))
Binding Specificity
All epitopes for RNF216 antibodies
N-Term
Reactivity
All reactivities for RNF216 antibodies
Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit
Host
All hosts for RNF216 antibodies
Rabbit
Clonality
All clonalities for RNF216 antibodies
Polyclonal
Conjugate
All conjugates for RNF216 antibodies
This RNF216 antibody is un-conjugated
Application
All applications for RNF216 antibodies
Western Blotting (WB)
Sequence
IVNPRLEQKV IILGENGLLF PESEPLEVQN QSSEDSETEL LSNPGEPAAS
Predicted Reactivity
Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
Characteristics
This is a rabbit polyclonal antibody against Rnf216. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Rnf216
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for RNF216
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Target
RNF216
(Ring Finger Protein 216 (RNF216))
Alternative Name
Rnf216 (RNF216 Products )
Synonyms
RGD1565135 antibody, TRIAD3 antibody, RNF216 antibody, zin antibody, u7i1 antibody, triad3 antibody, ubce7ip1 antibody, MGC147026 antibody, 2810055g22rik antibody, 2810055G22Rik antibody, AI647468 antibody, AU019462 antibody, C86502 antibody, F830018F18Rik antibody, UIP83 antibody, Ubce7ip1 antibody, CAHH antibody, U7I1 antibody, UBCE7IP1 antibody, ZIN antibody, ring finger protein 216 antibody, Rnf216 antibody, RNF216 antibody, rnf216 antibody
Background
Rnf216 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. It promotes degradation of TRAF3, TLR4 and TLR9. It contributes to the regulation of antiviral responses. It down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production and promotes TNF and RIP mediated apoptosis. Protein Interaction Partner: Ube2l3, Protein Size: 853
Molecular Weight
93 kDa
Gene ID
108086
UniProt
P58283
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