MAP3K10 antibody (C-Term)

Catalog No. ABIN2774283

The Rabbit Polyclonal anti-MAP3K10 antibody has been validated for WB. It is suitable to detect MAP3K10 in samples from Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig and Pig.

Quick Overview for MAP3K10 antibody (C-Term) (ABIN2774283)

Target: MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAP3K10 Antibody

Binding Specificity: C-Term

Sequence: TLTFAPRPRP AASRPRLDPW KLVSFGRTLT ISPPSRPDTP ESPGPPSVQP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MAP3K10. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAP3K10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 954 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAP3K10

Target: MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))

Alternative Name: MAP3K10

Background: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
Alias Symbols: MEKK10, MLK2, MST
Protein Interaction Partner: MAPK9, MAPK1, MAP3K10, MAPK14, GARS, COPS2, KIAA1804, ABL2, SH3RF1, CNKSR1, YWHAE, RACGAP1, KIF3A, DNM1L, KIF3B, DLG4, KIFAP3, MAP2K4, TUBB, PHB, HTT, CLTC, CDC42, CEACAM1, HGS, DNM1, KRTAP3-4P, KIF17, MAPK8IP2, MAPK8IP1, RAC1, HPCA, NEUROD1,
Protein Size: 954

Molecular Weight: 104 kDa

Gene ID: 4294

NCBI Accession: NM_002446, NP_002437

UniProt: Q02779