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VPS4B antibody (N-Term)

vps4b Reactivity: Human, Rat, Rabbit, Dog, Guinea Pig, Horse, Cow WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774320
  • Target See all VPS4B (vps4b) Antibodies
    VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 42
    • 17
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Rabbit, Dog, Guinea Pig, Horse, Cow
    Host
    • 41
    • 1
    Rabbit
    Clonality
    • 42
    Polyclonal
    Conjugate
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VPS4B antibody is un-conjugated
    Application
    • 37
    • 22
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    EKLKEYLKNK EKKAQKPVKE GQPSPADEKG NDSDGEGESD DPEKKKLQNQ
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 86%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against VPS4B. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product vps4b Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 444 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
    Alternative Name
    VPS4B (vps4b Products)
    Synonyms
    zgc:63682 antibody, vps4a antibody, SKD1 antibody, SKD1B antibody, VPS4-2 antibody, 8030489C12Rik antibody, Skd1 antibody, vacuolar protein sorting 4 homolog B antibody, vacuolar protein sorting 4 homolog B S homeolog antibody, vacuolar protein sorting 4b homolog B (S. cerevisiae) antibody, vacuolar protein sorting 4 homolog B (S. cerevisiae) antibody, vacuolar protein sorting 4B antibody, Vps4b antibody, vps4b.S antibody, vps4b antibody, VPS4B antibody
    Background
    The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18, the gene for the other resides on chromosome 16.
    Alias Symbols: MIG1, SKD1, SKD1B, VPS4-2
    Protein Interaction Partner: ZFYVE19, CHMP5, UBC, HTRA2, CHMP4A, TTLL12, AHCYL1, SSSCA1, YAP1, UBE4B, PDCD6IP, USP34, VPS26A, USP8, ZPR1, NUP214, TYMS, RAB5B, IGBP1, TTC9C, ZNF585B, UBQLN4, UBXN1, UBQLN1, CUL3, CHMP2A, CHMP1A, ELAVL1, BABAM1, CHMP1B, VPS4A, VPS4, LIP5,
    Protein Size: 444
    Molecular Weight
    49 kDa
    Gene ID
    9525
    NCBI Accession
    NM_004869, NP_004860
    UniProt
    O75351
    Pathways
    Microtubule Dynamics, CXCR4-mediated Signaling Events
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