VPS4B antibody (N-Term)
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- Target See all VPS4B (vps4b) Antibodies
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Rabbit, Dog, Guinea Pig, Horse, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VPS4B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EKLKEYLKNK EKKAQKPVKE GQPSPADEKG NDSDGEGESD DPEKKKLQNQ
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 86%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against VPS4B. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product vps4b Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 444 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
- Alternative Name
- VPS4B (vps4b Products)
- Synonyms
- zgc:63682 antibody, vps4a antibody, SKD1 antibody, SKD1B antibody, VPS4-2 antibody, 8030489C12Rik antibody, Skd1 antibody, vacuolar protein sorting 4 homolog B antibody, vacuolar protein sorting 4 homolog B S homeolog antibody, vacuolar protein sorting 4b homolog B (S. cerevisiae) antibody, vacuolar protein sorting 4 homolog B (S. cerevisiae) antibody, vacuolar protein sorting 4B antibody, Vps4b antibody, vps4b.S antibody, vps4b antibody, VPS4B antibody
- Background
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The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18, the gene for the other resides on chromosome 16.
Alias Symbols: MIG1, SKD1, SKD1B, VPS4-2
Protein Interaction Partner: ZFYVE19, CHMP5, UBC, HTRA2, CHMP4A, TTLL12, AHCYL1, SSSCA1, YAP1, UBE4B, PDCD6IP, USP34, VPS26A, USP8, ZPR1, NUP214, TYMS, RAB5B, IGBP1, TTC9C, ZNF585B, UBQLN4, UBXN1, UBQLN1, CUL3, CHMP2A, CHMP1A, ELAVL1, BABAM1, CHMP1B, VPS4A, VPS4, LIP5,
Protein Size: 444 - Molecular Weight
- 49 kDa
- Gene ID
- 9525
- NCBI Accession
- NM_004869, NP_004860
- UniProt
- O75351
- Pathways
- Microtubule Dynamics, CXCR4-mediated Signaling Events
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