MUSK antibody (N-Term)

Catalog No. ABIN2774361

Product Details anti-MUSK Antibody

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUSK antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ENSRIAVLES GSLRIHNVQK EDAGQYRCVA KNSLGTAYSK VVKLEVEVFA

Predicted Reactivity: Cow: 93%, Dog: 83%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against MUSK. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 773 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MUSK

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Alternative Name: MUSK (MUSK Products)

Synonyms: unp antibody, fj98e12 antibody, zgc:63467 antibody, wu:fj98e12 antibody, si:dz46m7.2 antibody, si:dz57f23.3 antibody, si:busm1-57f23.3 antibody, musk-A antibody, MuSK antibody, MUSK antibody, Mdk4 antibody, Mlk antibody, Nsk1 antibody, Nsk2 antibody, Nsk3 antibody, muscle antibody, muscle associated receptor tyrosine kinase antibody, muscle, skeletal, receptor tyrosine kinase antibody, muscle associated receptor tyrosine kinase S homeolog antibody, MUSK antibody, musk antibody, musk.S antibody, Musk antibody

Background: This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.
Alias Symbols: MGC126323, MGC126324
Protein Interaction Partner: HSP90AA1, NEDD8, PDZRN3, UBC, SYNE1, DOK7, COLQ, RAPSN,
Protein Size: 773

Molecular Weight: 85 kDa

Gene ID: 4593

NCBI Accession: NM_001166281, NP_001159753

Pathways: RTK Signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development