PARD6B antibody (N-Term)

Catalog No. ABIN2775631

Product Details anti-PARD6B Antibody

Target: PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARD6B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MNRSHRHGAG SGCLGTMEVK SKFGAEFRRF SLERSKPGKF EEFYGLLQHV

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PARD6B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PARD6B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 372 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PARD6B

Target: PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))

Alternative Name: PARD6B (PARD6B Products)

Synonyms: PARD6B antibody, AV025615 antibody, Par6b antibody, PAR6B antibody, par-6 antibody, par6 antibody, pard6beta antibody, si:dkey-192i18.6 antibody, PAR-6 antibody, PAR-6B antibody, par-6 family cell polarity regulator beta antibody, par-6 family cell polarity regulator beta S homeolog antibody, par-6 partitioning defective 6 homolog beta (C. elegans) antibody, PARD6B antibody, Pard6b antibody, pard6b.S antibody, pard6b antibody

Background: This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.
Alias Symbols: PAR6B
Protein Interaction Partner: CEP76, GMCL1, RHOJ, PRKCI, GOLGA2, CDC42, CRB3, WDR83, NPM1, UBC, APP, PRKCZ, PARD6G, PARD3, PARD6A, YWHAH, LLGL1, LLGL2, DMBT1, PARD3B, MPP5, RHOQ, PNMA1, HTRA1, RAC1, YWHAB, YWHAZ, TCP10, PRKCG,
Protein Size: 372

Molecular Weight: 41 kDa

Gene ID: 84612

NCBI Accession: NM_032521, NP_115910

UniProt: Q9BYG5

Pathways: Cell-Cell Junction Organization