ARC (Middle Region) antibody

Catalog No. ABIN2775851

Product Details

Target: ARC

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Sequence: TIANLERWVK REMHVWREVF YRLERWADRL ESMGGKYPVG SEPARHTVSV

Predicted Reactivity: Cow: 85%, Goat: 85%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against Arc. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 396 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: ARC

Synonyms: activity regulated cytoskeleton associated protein antibody, Arc antibody

Background: Arc is required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.
Alias Symbols: Arc3.1, C86064, arg3.1
Protein Interaction Partner: Dlg4, Grin2b, Grin1,
Protein Size: 396

Molecular Weight: 45 kDa

Gene ID: 11838

NCBI Accession: NM_001106278, NP_001099748

UniProt: Q7LC44