GABRB2 antibody (N-Term)

Catalog No. ABIN2776115

The Rabbit Polyclonal anti-GABRB2 antibody (ABIN2776115) specifically detects GABRB2 in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit and Sheep samples.

Quick Overview for GABRB2 antibody (N-Term) (ABIN2776115)

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABRB2 Antibody

Binding Specificity: N-Term

Sequence: DNRVADQLWV PDTYFLNDKK SFVHGVTVKN RMIRLHPDGT VLYGLRITTT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GABRB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABRB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 474 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABRB2

Target: GABRB2 (gamma-aminobutyric Acid (GABA) A Receptor, beta 2 (GABRB2))

Alternative Name: GABRB2

Background: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion.
Alias Symbols: MGC119386, MGC119388, MGC119389
Protein Interaction Partner: UBC, UBQLN1, TRAK2, ARFGEF2, PRKCB, PPP3CA,
Protein Size: 474

Molecular Weight: 54 kDa

Gene ID: 2561

NCBI Accession: NM_000813, NP_000804

UniProt: P47870

Pathways: Sensory Perception of Sound, Synaptic Membrane