EPH Receptor B6 antibody (Middle Region)

Catalog No. ABIN2776160

The Rabbit Polyclonal anti-EPH Receptor B6 antibody has been validated for WB. It is suitable to detect EPH Receptor B6 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for EPH Receptor B6 antibody (Middle Region) (ABIN2776160)

Target: EPH Receptor B6 (EPHB6)

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPH Receptor B6 Antibody

Binding Specificity: Middle Region

Sequence: VRLFSYTCPA VLRSFASFPE TQASGAGGAS LVAAVGTCVA HAEPEEDGVG

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EPHB6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of HUMAN EPHB6

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EPH Receptor B6

Target: EPH Receptor B6 (EPHB6)

Alternative Name: EPHB6

Background: This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants.
Protein Interaction Partner: NOTCH2NL, INCA1, NIF3L1, TRIM39, TCF4, REL, HSP90AA1, EPHB4, BCL6, HDHD2, CRKL, EPHB1, EFNB2, SAT1, CBL, CRK, MLLT4, GRB2,
Protein Size: 540

Molecular Weight: 59 kDa

Gene ID: 2051

Pathways: RTK Signaling, Hormone Transport