CLCN6 antibody (C-Term)
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- Target See all CLCN6 Antibodies
- CLCN6 (Chloride Channel, Voltage-Sensitive 6 (CLCN6))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CLCN6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PQFQSISLRK IQFNFPYFRS DRDKRDFVSA GAAAGVAAAF GAPIGGTLFS
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against CLCN6. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CLCN6
- Top Product
- Discover our top product CLCN6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 353 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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A quantitative assay for lysosomal acidification rates in human osteoclasts." in: Assay and drug development technologies, Vol. 9, Issue 2, pp. 157-64, (2011) (PubMed).
: "Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 13, Issue 9, pp. 483-92, (2002) (PubMed).
: "
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A quantitative assay for lysosomal acidification rates in human osteoclasts." in: Assay and drug development technologies, Vol. 9, Issue 2, pp. 157-64, (2011) (PubMed).
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- Target
- CLCN6 (Chloride Channel, Voltage-Sensitive 6 (CLCN6))
- Alternative Name
- CLCN6 (CLCN6 Products)
- Synonyms
- CLC-6 antibody, AI850629 antibody, CLCN6 antibody, wu:fb95f01 antibody, DKFZp469B244 antibody, DKFZp469L0417 antibody, chloride voltage-gated channel 6 antibody, chloride channel, voltage-sensitive 6 antibody, chloride channel 6 antibody, chloride transport protein 6 antibody, CLCN6 antibody, Clcn6 antibody, clcn6 antibody, LOC579870 antibody
- Background
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The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This gene is in close vicinity to two other kidney-specific chloride channel genes, CLCNKA and CLCNKB.
Alias Symbols: CLC-6
Protein Interaction Partner: UBC, PPP2R1A,
Protein Size: 353 - Molecular Weight
- 39 kDa
- Gene ID
- 1185
- NCBI Accession
- NM_021736, NP_068504
- UniProt
- Q5SNX3
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