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GSTM2 antibody (N-Term)

GSTM2 Reactivity: Human, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777010
  • Target See all GSTM2 Antibodies
    GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 21
    • 14
    • 8
    Human, Zebrafish (Danio rerio)
    Host
    • 23
    • 5
    Rabbit
    Clonality
    • 23
    • 5
    Polyclonal
    Conjugate
    • 18
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GSTM2 antibody is un-conjugated
    Application
    • 18
    • 13
    • 9
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    TQSNAILRYI ARKHNLCGES EKEQIREDIL ENQFMDSRMQ LAKLCYDPDF
    Predicted Reactivity
    Human: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against GSTM2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human GSTM2
    Top Product
    Discover our top product GSTM2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Antigen size: 218 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))
    Alternative Name
    GSTM2 (GSTM2 Products)
    Synonyms
    GSTA4 antibody, GST4 antibody, GSTM antibody, GSTM2-2 antibody, GTHMUS antibody, Gstb-2 antibody, Gstb2 antibody, GSTIV antibody, glutathione S-transferase mu 2 antibody, glutathione S-transferase mu 2 (muscle) antibody, glutathione S-transferase Mu 2 antibody, glutathione S-transferase, mu 2 antibody, glutathione S-transferase 2 antibody, Glutathione S-transferase 4 antibody, Gstm2 antibody, GSTM2 antibody, LOC100732167 antibody, gst2 antibody, gst-4 antibody
    Background
    At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM2 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
    Alias Symbols: GST4, GSTM, GSTM2-2, GTHMUS, MGC117303
    Protein Interaction Partner: UBC, GSTM3, GSTM2, GSTM1,
    Protein Size: 218
    Molecular Weight
    26 kDa
    Gene ID
    2946
    NCBI Accession
    NM_000848, NP_000839
    UniProt
    P28161
    Pathways
    Negative Regulation of Transporter Activity
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