MYB antibody (C-Term)

Catalog No. ABIN2777183

Product Details anti-MYB Antibody

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Binding Specificity: C-Term

Reactivity: Human, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VPKNRSLASP LQPCSSTWEP ASCGKMEEQM TSSSQARKYV NAFSARTLVM

Predicted Reactivity: Dog: 80%, Human: 100%, Pig: 93%

Characteristics: This is a rabbit polyclonal antibody against MYB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MYB

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Alternative Name: MYB (MYB Products)

Synonyms: Cmyb antibody, c-myb antibody, c-myb_CDS antibody, efg antibody, AI550390 antibody, M16449 antibody, cmyb antibody, xmyb antibody, MYB proto-oncogene, transcription factor antibody, myeloblastosis oncogene antibody, MYB proto-oncogene, transcription factor S homeolog antibody, v-myb avian myeloblastosis viral oncogene homolog antibody, MYB antibody, Myb antibody, myb.S antibody, myb antibody

Background: This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
Alias Symbols: Cmyb, c-myb, c-myb_CDS, efg
Protein Interaction Partner: UBC, ERC2, UPF2, PPM1K, MYOZ2, SUMO1, SUMO2, CCND3, EP300, RBX1, FBXW5, PIAS1, CUL4A, UBE2I, DDB1, TRAF6, STAT5A, GATA3, KAT5, Fbxw7, CREBBP, LEF1, RPL4, KAT2B, CHD3, SIN3A, TRIM28, NCOR1, SKI, HIPK2, NLK, SP100, HLF, PARP1, ASH2L, RBBP5, KMT2A, MEN1, WDR
Protein Size: 640

Molecular Weight: 70 kDa

Gene ID: 4602

NCBI Accession: NM_005375, NP_005366

UniProt: P10242

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process