U2AF2 antibody (C-Term)
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- Target See all U2AF2 (U2AF59) Antibodies
- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This U2AF2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TEVLCLMNMV LPEELLDDEE YEEIVEDVRD ECSKYGLVKS IEIPRPVDGV
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against U2AF2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human U2AF2
- Top Product
- Discover our top product U2AF59 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 471 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
- Alternative Name
- U2AF2 (U2AF59 Products)
- Synonyms
- U2AF65 antibody, 65kDa antibody, u2af65 antibody, U2AF2 antibody, DDBDRAFT_0186947 antibody, DDBDRAFT_0233353 antibody, DDB_0186947 antibody, DDB_0233353 antibody, zgc:110115 antibody, U2 small nuclear RNA auxiliary factor 2 antibody, U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 antibody, U2 small nuclear RNA auxiliary factor 2 S homeolog antibody, RNA recognition motif-containing protein RRM antibody, Splicing factor U2AF 65 kDa subunit antibody, U2 small nuclear RNA auxiliary factor 2a antibody, U2AF2 antibody, U2af2 antibody, u2af2.S antibody, u2af2 antibody, u2af2a antibody
- Background
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U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly.
Alias Symbols: U2AF65
Protein Interaction Partner: THAP1, PUF60, U2AF1, SNRPA, AES, DACH1, SUMO3, UBC, SUZ12, EED, TERF1, EZH2, RNF2, PRPF40A, TCERG1, APBB1, PIN1, SH3RF2, SRPK2, SRPK1, SF1, SRSF1, RBM39, QKI, SCAF11, PRPF3, RBM10, RBM4, SMAD5, IL7R, HNRNPK, HNRNPD, HLA-DMA, SUGP1, CCAR1, SAP30BP, RBFOX2,
Protein Size: 471 - Molecular Weight
- 53 kDa
- Gene ID
- 11338
- NCBI Accession
- NM_001012478, NP_001012496
- UniProt
- Q80XR5
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