CDK4 antibody (C-Term)

Catalog No. ABIN2779310

The Rabbit Polyclonal anti-CDK4 antibody (ABIN2779310) specifically detects CDK4 in WB and IHC. The antibody is reactive with Human, Rat, Sheep, Pig, Dog, Cow, Rabbit, Guinea Pig and Horse samples.

Quick Overview for CDK4 antibody (C-Term) (ABIN2779310)

Target: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Reactivity: Human, Rat, Sheep, Pig, Dog, Cow, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CDK4 Antibody

Binding Specificity: C-Term

Sequence: PRPVQSVVPE MEESGAQLLL EMLTFNPHKR ISAFRALQHS YLHKDEGNPE

Predicted Reactivity: Cow: 75%, Dog: 83%, Guinea Pig: 83%, Horse: 83%, Human: 100%, Pig: 92%, Rabbit: 83%, Rat: 83%, Sheep: 75%

Characteristics: This is a rabbit polyclonal antibody against CDK4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 303 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDK4

Target: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Alternative Name: CDK4

Background: Cdk4 is probably involved in the control of the cell cycle.
Alias Symbols: CMM3, MGC14458, PSK-J3
Protein Interaction Partner: RELA, HOOK1, CDKN2D, CDKN2C, CCND3, CCND1, CDKN1A, CCNA2, FKBP5, CDC37, CDKN1B, CDK4, UBC, CDKN2B, CDKN2A, CDK13, TARDBP, CAMK1, PTMA, CDK6, RB1, HSP90AB1, HSP90AA1, HSPA8, KLHL32, TRAP1, UCHL1, SKP1, SHOX2, RBL2, RBL1, PGD, OTX2, MYC, MCM2, IL15RA, GLI1,
Protein Size: 303

Molecular Weight: 34 kDa

Gene ID: 1019

NCBI Accession: NM_000075, NP_000066

UniProt: P11802

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size