MYCN antibody (C-Term)
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- Target See all MYCN Antibodies
- MYCN (N-Myc Proto-Oncogene Protein (MYCN))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MYCN antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EDAPPQKKIK SEASPRPLKS VIPPKAKSLS PRNSDSEDSE RRRNHNILER
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 77%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against MYCN. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human MYCN
- Top Product
- Discover our top product MYCN Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 464 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MYCN (N-Myc Proto-Oncogene Protein (MYCN))
- Alternative Name
- MYCN (MYCN Products)
- Synonyms
- MODED antibody, MYCNOT antibody, N-myc antibody, NMYC antibody, ODED antibody, bHLHe37 antibody, Nmyc antibody, Nmyc-1 antibody, Nmyc1 antibody, c-nmyc antibody, Nmuc1 antibody, fb57a02 antibody, nmyc1 antibody, wu:fb57a02 antibody, zgc:85706 antibody, XN-myc antibody, XNmyc antibody, mycn antibody, mycn-a antibody, mycn-b antibody, mycna antibody, xN-myc1 antibody, MYCN proto-oncogene, bHLH transcription factor antibody, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog antibody, v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived antibody, olfactory receptor 8S1 antibody, MYCN proto-oncogene, bHLH transcription factor S homeolog antibody, MYCN antibody, Mycn antibody, LOC515887 antibody, mycn antibody, mycn.S antibody
- Background
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MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas
Alias Symbols: NMYC, ODED, MODED, N-myc, bHLHe37
Protein Interaction Partner: TRIM32, UBC, HDAC5, NMI, MAX, CDKN2A, GRK5, ZBTB17, SIRT1, YEATS4, CSNK1E, FBXW7, PIAS2, AURKA, SP1, NTRK1, NGFR, HDAC2, CSNK2A1, YAF2, MXD1, CSNK2A2, SLC1A2,
Protein Size: 464 - Molecular Weight
- 50 kDa
- Gene ID
- 4613
- NCBI Accession
- NM_005378, NP_005369
- UniProt
- P04198
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