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NOTO antibody (N-Term)

NOTO Reactivity: Mouse, Human, Cow, Rat, Dog, Guinea Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779813
  • Target See all NOTO Antibodies
    NOTO (Notochord Homeobox (NOTO))
    Binding Specificity
    • 2
    • 2
    N-Term
    Reactivity
    Mouse, Human, Cow, Rat, Dog, Guinea Pig, Rabbit
    Host
    • 3
    Rabbit
    Clonality
    • 3
    Polyclonal
    Conjugate
    • 3
    This NOTO antibody is un-conjugated
    Application
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    VQPGSLRPCP GAVSPVVPRR LARGRLESSF SVEAILARPK TRELAATSLP
    Predicted Reactivity
    Cow: 86%, Dog: 85%, Guinea Pig: 93%, Human: 93%, Mouse: 100%, Rabbit: 92%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against Noto. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the n terminal region of mouse Noto
    Top Product
    Discover our top product NOTO Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 240 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NOTO (Notochord Homeobox (NOTO))
    Alternative Name
    Noto (NOTO Products)
    Synonyms
    Xnot-2 antibody, Xnot2 antibody, not antibody, nota antibody, noto antibody, RGD1562910 antibody, Xnot antibody, Flh antibody, MmNot antibody, Not antibody, tc antibody, Znot antibody, flh antibody, notochord homeobox antibody, notochord homeobox S homeolog antibody, NOTO antibody, not.S antibody, Noto antibody, not antibody, noto antibody
    Background
    Noto is a transcription regulator acting downstream of both FOXA2 and T during notochord development.Noto is required for node morphogenesis.Noto is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning, acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate.
    Alias Symbols: Flh, MmNot, Not, tc
    Protein Size: 240
    Molecular Weight
    26 kDa
    Gene ID
    384452
    NCBI Accession
    NM_001007472, NP_001007473
    UniProt
    A8MTQ0
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