PTF1A antibody (N-Term)

Catalog No. ABIN2780011

Product Details anti-PTF1A Antibody

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTF1A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FPSPYFDEED FFTDQSSRDP LEDSDELLGD EQAEVEFLSH QLHEYCYRDG

Predicted Reactivity: Cow: 93%, Dog: 86%, Horse: 92%, Human: 93%, Mouse: 100%, Pig: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Ptf1a. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Ptf1a

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 324 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTF1A

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Alternative Name: Ptf1a (PTF1A Products)

Synonyms: PTF1A antibody, PTF1 antibody, si:zc142h2.2 antibody, zgc:112216 antibody, Ptf1a/p48 antibody, XPtf1a antibody, PTF1-p48 antibody, bHLHa29 antibody, PTF1p48 antibody, pancreas specific transcription factor, 1a antibody, PTF1A antibody, ptf1a antibody, Ptf1a antibody

Background: Ptf1a is a transcriptional activator. It binds to the E-box consensus sequence 5'-CANNTG-3' and may play a role in early and late pancreas development and differentiation. Ptf1a plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates and may be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. It is required for the formation of pancreatic acinar and ductal cells. and plays an important role in cerebellar development.
Alias Symbols: PTF1-p48, PTF1p48, bHLHa29
Protein Interaction Partner: Rbpj,
Protein Size: 324

Molecular Weight: 35 kDa

Gene ID: 19213

NCBI Accession: NM_018809, NP_061279

UniProt: Q9QX98

Pathways: Retinoic Acid Receptor Signaling Pathway