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CDK5 antibody (Cyclin-Dependent Kinase 5) (C-Term) Primary Antibody

CDK5 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Saccharomyces cerevisiae, Sheep, Zebrafish (Danio rerio) IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780626
$339.00
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100 μL
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  • Target
    CDK5
    Binding Specificity
    C-Term
    • 22
    • 15
    • 14
    • 14
    • 9
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Saccharomyces cerevisiae, Sheep, Zebrafish (Danio rerio)
    • 159
    • 112
    • 100
    • 17
    • 15
    • 14
    • 14
    • 13
    • 13
    • 11
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This CDK5 antibody is un-conjugated
    • 99
    • 11
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Application
    Immunohistochemistry (IHC), Western Blotting (WB)
    • 117
    • 55
    • 27
    • 26
    • 23
    • 21
    • 19
    • 14
    • 14
    • 4
    • 3
    • 3
    • 1
    Sequence
    MYPATTSLVN VVPKLNATGR DLLQNLLKCN PVQRISAEEA LQHPYFSDFC
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 79%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against CDK5. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CDK5
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 292 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CDK5
    Alternative Name
    CDK5 (CDK5 Antibody Abstract)
    Synonyms
    PSSALRE, AW048668, Crk6, CDK5, CG8203, DmCdk5, Dmel\\CG8203, cdk5, zgc:101604, cyclin dependent kinase 5, cyclin-dependent kinase 5, Cyclin-dependent kinase 5, cyclin-dependent kinase 5 L homeolog, Cyclin-dependent-like kinase 5, CDK5, Cdk5, cdk5, cdk5.L, cdk-5
    Background
    CDK5 is probably involved in the control of the cell cycle. CDK5 can interact with d1 and d3-type G1 cyclins and phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. CDK5 can also interacts with p35 which activates the kinase
    Alias Symbols: PSSALRE
    Protein Interaction Partner: CHFR, CCND2, CDKN1A, EGFR, UBC, DCLK3, CDK5, CCNE1, CDK5R1, CABLES1, CABLES2, STIP1, CDKN1B, CCND3, CCNB1, C2CD5, KIAA0195, FIBP, PPARG, CDK18, HSP90AB1, HSP90AA1, HIST1H1B, GLUD1, CDK3, CDC25B, CCT6A, CCNA2, CCT3, TCP1, CCT5, CDC37, CCT8, CCT2, CCT4, CCT
    Protein Size: 292
    Molecular Weight
    33 kDa
    Gene ID
    1020
    NCBI Accession
    NM_004935, NP_004926
    UniProt
    Q00535
    Pathways
    Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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