ARC (C-Term) antibody

Catalog No. ABIN2780970

Product Details

Target: ARC

Binding Specificity: C-Term

Reactivity: Human, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Sequence: RHPLPKTLEQ LIQRGMEVQD DLEQAAEPAG PHLPVEDEAE TLTPAPNSES

Predicted Reactivity: Guinea Pig: 86%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ARC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ARC

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: ARC

Synonyms: activity regulated cytoskeleton associated protein antibody, Arc antibody

Background: ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. It is required for homeostatic synaptic scaling of AMPA receptors. ARC plays a role in the regulation of cell morphology and cytoskeletal organization and is required in the stress fiber dynamics and cell migration.
Alias Symbols: Arg3.1
Protein Interaction Partner: UBE3A, UBC, KRT15,
Protein Size: 396

Molecular Weight: 43 kDa

Gene ID: 23237

NCBI Accession: NM_015193, NP_056008

UniProt: Q7LC44