SLC25A19 antibody (Middle Region)
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- Target See all SLC25A19 Antibodies
- SLC25A19 (Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 (SLC25A19))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC25A19 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VHRGSVYDAR EFSVHFVCGG LAACMATLTV HPVDVLRTRF AAQGEPKVYN
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Yeast: 77%
- Characteristics
- This is a rabbit polyclonal antibody against SLC25A19. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SLC25A19
- Top Product
- Discover our top product SLC25A19 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 320 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SLC25A19 (Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 (SLC25A19))
- Alternative Name
- SLC25A19 (SLC25A19 Products)
- Synonyms
- zgc:111878 antibody, 2900089E13Rik antibody, DNC antibody, MUP1 antibody, TPC antibody, MCPHA antibody, THMD3 antibody, THMD4 antibody, solute carrier family 25 member 19 antibody, solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 antibody, Slc25a19 antibody, slc25a19 antibody, SLC25A19 antibody
- Background
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This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
Alias Symbols: DNC, MCPHA, MUP1, TPC, THMD3, THMD4
Protein Interaction Partner: UBC,
Protein Size: 320 - Molecular Weight
- 35 kDa
- Gene ID
- 60386
- NCBI Accession
- NM_021734, NP_068380
- UniProt
- Q9HC21
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