Solute Carrier Family 25 (Mitochondrial Oxodicarboxylate Carrier), Member 21 (Slc25a21) (N-Term) antibody

Details for Product No. ABIN2781689, Supplier: Log in to see
Antigen
  • zgc:153387
  • ODC
  • ODC1
  • Odc1
  • 9930033G19Rik
  • A630030I10
  • BB158148
  • solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
  • solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 L homeolog
  • solute carrier family 25 member 21
  • solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
  • slc25a21
  • slc25a21.L
  • SLC25A21
  • Slc25a21
Epitope
N-Term
6
3
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Yeast (Saccharomyces cerevisiae), Zebrafish (Danio rerio)
28
11
11
3
3
3
3
3
2
2
2
2
2
1
1
Host
Rabbit
21
7
Clonality
Polyclonal
Application
Western Blotting (WB)
25
16
12
9
4
4
4
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SLC25A21
Blocking Peptide Blocking peptide for this product available: ABIN983898
Sequence FYKGILPPIL AETPKRAVKF FTFEQYKKLL GYVSLSPALT FAIAGLGSGL
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against SLC25A21. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SLC25A21 (Slc25a21 Antibody Abstract)
Background SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM]. Sequence Note: removed 1 base from the 3' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2023 AJ278148.1 1-2023
Alias Symbols: MGC126570, ODC, ODC1
Protein Interaction Partner: FBXO6,
Protein Size: 299
Molecular Weight 33 kDa
Gene ID 89874
NCBI Accession NM_030631, NP_085134
UniProt Q9BQT8
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 299 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Solute Carrier Family 25 (Mitochondrial Oxodicarboxylate Carrier), Member 21 (Slc25a21) (N-Term) antibody (ABIN2781689) WB Suggested Anti-SLC25A21 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 ...
Background publications Fiermonte, Dolce, Palmieri, Ventura, Runswick, Palmieri, Walker: "Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location." in: The Journal of biological chemistry, Vol. 276, Issue 11, pp. 8225-30, 2001 (PubMed).

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