PDE3B antibody (Middle Region)

Catalog No. ABIN2781829

This Rabbit Polyclonal antibody specifically detects PDE3B in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for PDE3B antibody (Middle Region) (ABIN2781829)

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE3B Antibody

Binding Specificity: Middle Region

Purpose: PDE3B Antibody - middle region

Sequence: SRPEYNFLLH LDHVEFKRFR FLVIEAILAT DLKKHFDFLA EFNAKANDVN

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PDE3B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDE3B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44359-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE3B

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Alternative Name: PDE3B

Background:

Background Information: PDE3B belongs to the cyclic nucleotide phosphodiesterase family. It may play a role in fat metabolism.

Gene Name: Phosphodiesterase 3B, cGMP-inhibited

Alternative Symbols: HcGIP1, cGIPDE1

Protein Name: cGMP-inhibited 3',5'-cyclic phosphodiesterase B

Molecular Weight: 124 kDa

Gene ID: 5140

NCBI Accession: NP_000913

UniProt: Q13370

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process