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CISD2 antibody (CDGSH Iron Sulfur Domain 2) (N-Term) Primary Antibody

CISD2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781919
$229.00
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100 μL
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  • Target
    CISD2
    Binding Specificity
    N-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This CISD2 antibody is un-conjugated
    Application
    Western Blotting (WB)
    Sequence
    VLESVARIVK VQLPAYLKRL PVPESITGFA RLTVSEWLRL LPFLGVLALL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
    Characteristics
    This is a rabbit polyclonal antibody against CISD2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CISD2
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 135 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CISD2
    Alternative Name
    CISD2 (CISD2 Antibody Abstract)
    Synonyms
    ERIS, Miner1, NAF-1, WFS2, ZCD2, 1500009M05Rik, 1500026J14Rik, 1500031D15Rik, AI848398, B630006A20Rik, Noxp70, Zcd2, RGD1566242, zgc:64148, eris, miner1, wfs2, zcd2, cisd2, CDGSH iron sulfur domain 2, CDGSH iron sulfur domain 2 L homeolog, CDGSH iron sulfur domain 2 S homeolog, CISD2, Cisd2, cisd2, cisd2.L, cisd2.S
    Background
    CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum. It binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2 (WFS2).
    Alias Symbols: ERIS, Miner1, WFS2, ZCD2, NAF-1
    Protein Interaction Partner: UBC, LMNA, APP, SPP1, BCL2, ELAVL1,
    Protein Size: 135
    Molecular Weight
    15 kDa
    Gene ID
    493856
    NCBI Accession
    NM_001008388, NP_001008389
    UniProt
    Q8N5K1
    Pathways
    Activation of Innate immune Response
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