CISD2 antibody (CDGSH Iron Sulfur Domain 2) (N-Term)

Details for Product anti-CISD2 Antibody No. ABIN2781919
Target
Binding Specificity
N-Term
4
2
2
1
1
1
Reactivity
Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
14
7
4
1
1
1
1
1
1
1
1
Host
Rabbit
14
1
Clonality
Polyclonal
Conjugate
This CISD2 antibody is un-conjugated
1
1
1
Application
Western Blotting (WB)
12
12
5
3
2
1
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CISD2
Blocking Peptide Blocking peptide for this product available: ABIN974996
Sequence VLESVARIVK VQLPAYLKRL PVPESITGFA RLTVSEWLRL LPFLGVLALL
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
Characteristics This is a rabbit polyclonal antibody against CISD2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Target
Alternative Name CISD2 (CISD2 Antibody Abstract)
Background CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum. It binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2 (WFS2).
Alias Symbols: ERIS, Miner1, WFS2, ZCD2, NAF-1
Protein Interaction Partner: UBC, LMNA, APP, SPP1, BCL2, ELAVL1,
Protein Size: 135
Molecular Weight 15 kDa
Gene ID 493856
NCBI Accession NM_001008388, NP_001008389
UniProt Q8N5K1
Pathways Activation of Innate immune Response
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 135 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Images
Image no. 1 for anti-CDGSH Iron Sulfur Domain 2 (CISD2) (N-Term) antibody (ABIN2781919) WB Suggested Anti-CISD2 Antibody Titration: 0.2-1 ug/ml Positive Control: Transfec...