WNT6 antibody (Middle Region)
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- Target See all WNT6 Antibodies
- WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This WNT6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ERFHGASRVM GTNDGKALLP AVRTLKPPGR ADLLYAADSP DFCAPNRRTG
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against WNT6. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human WNT6
- Top Product
- Discover our top product WNT6 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 365 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
- Alternative Name
- WNT6 (WNT6 Products)
- Synonyms
- WNT6 antibody, si:dkey-31m21.2 antibody, Wnt6 antibody, AA409270 antibody, Wnt-6 antibody, Xwnt-6 antibody, wnt-6 antibody, wnt6-A antibody, xWnt6 antibody, Wnt family member 6 antibody, wingless-type MMTV integration site family, member 6b antibody, wingless-type MMTV integration site family, member 6 antibody, Wnt family member 6 S homeolog antibody, WNT6 antibody, Wnt6 antibody, wnt6b antibody, wnt6.S antibody
- Background
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The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.
Alias Symbols: -
Protein Interaction Partner: PORCN,
Protein Size: 365 - Molecular Weight
- 37 kDa
- Gene ID
- 7475
- NCBI Accession
- NM_006522, NP_006513
- UniProt
- Q9Y6F9
- Pathways
- WNT Signaling, Tube Formation
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