NEDD9 antibody (Middle Region)
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- Target See all NEDD9 Antibodies
- NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NEDD9 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- DLVDGINRLS FSSTGSTRSN MSTSSTSSKE SSLSASPAQD KRLFLDPDTA
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against NEDD9. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human NEDD9
- Top Product
- Discover our top product NEDD9 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 834 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))
- Alternative Name
- NEDD9 (NEDD9 Products)
- Synonyms
- NEDD9 antibody, CAS-L antibody, CAS2 antibody, CASL antibody, CASS2 antibody, HEF1 antibody, Cas-L antibody, CasL antibody, E230025G09Rik antibody, neural precursor cell expressed, developmentally down-regulated 9 antibody, neural precursor cell expressed, developmentally down-regulated gene 9 antibody, NEDD9 antibody, Nedd9 antibody
- Background
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Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers.
Alias Symbols: CAS-L, CASL, HEF1, dJ49G10.2, dJ761I2.1, CAS2, CASS2
Protein Interaction Partner: NFKBIA, NAB2, RFX6, PRR20A, BANP, RBPMS, BCAR3, TRIP6, TRIM27, REL, SMAD1, APP, CRK, UBC, PIK3CA, DIMT1, ELSPBP1, NEDD9, ITCH, CHAT, MICAL1, SH2D3C, SMAD3, BCAR1, PXN, CRKL, ZYX, SMAD2, PTK2B, PTK2, NCK1, ID2, RAPGEF1, PTPN12, CDH1, ABL1, PTPN11, LYN, LCK
Protein Size: 834 - Molecular Weight
- 93 kDa
- Gene ID
- 4739
- NCBI Accession
- NM_006403, NP_006394
- UniProt
- Q14511
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