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MBNL2 antibody (Middle Region)

MBNL2 Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784554
  • Target See all MBNL2 Antibodies
    MBNL2 (Muscleblind-Like 2 (MBNL2))
    Binding Specificity
    • 8
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 23
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse
    Host
    • 22
    • 1
    Rabbit
    Clonality
    • 22
    • 1
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This MBNL2 antibody is un-conjugated
    Application
    • 20
    • 14
    • 14
    • 13
    • 4
    • 1
    Western Blotting (WB)
    Sequence
    ENGRVIACFD SLKGRCSREN CKYLHPPTHL KTQLEINGRN NLIQQKTAAA
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against MBNL2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human MBNL2
    Top Product
    Discover our top product MBNL2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 255 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MBNL2 (Muscleblind-Like 2 (MBNL2))
    Alternative Name
    MBNL2 (MBNL2 Products)
    Synonyms
    1110002M11Rik antibody, AI047808 antibody, AI837313 antibody, AI849185 antibody, AL118326 antibody, MBLL antibody, R75232 antibody, mKIAA4072 antibody, wu:fj89c04 antibody, MBLL39 antibody, PRO2032 antibody, muscleblind like splicing factor 2 antibody, muscleblind-like splicing regulator 2 antibody, muscleblind like splicing regulator 2 antibody, Mbnl2 antibody, mbnl2 antibody, MBNL2 antibody
    Background
    MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
    Alias Symbols: DKFZp781H1296, MBLL, MBLL39, MGC120625, MGC120626, MGC120628, PRO2032, RP11-128N14.1
    Protein Interaction Partner: BMI1, ELAVL1, UBC,
    Protein Size: 255
    Molecular Weight
    28 kDa
    Gene ID
    10150
    NCBI Accession
    NM_005757, NP_005748
    UniProt
    O95205
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