LAMa4 antibody (C-Term)

Catalog No. ABIN2785769

Product Details anti-LAMa4 Antibody

Target: LAMa4 (Laminin, alpha 4 (LAMa4))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMa4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HCHPAGAPAP PRAVPHSSFS LSPPLSSPQC LESFTWARSV RKLEIKSFPL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against LAMA4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 120 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LAMa4

Target: LAMa4 (Laminin, alpha 4 (LAMa4))

Alternative Name: LAMA4 (LAMa4 Products)

Synonyms: si:dkey-119m7.3 antibody, si:busm1-189a20.2 antibody, CMD1JJ antibody, LAMA3 antibody, LAMA4*-1 antibody, RGD1560062 antibody, laminin subunit alpha 4 antibody, laminin, alpha 4 antibody, LAMA4 antibody, lama4 antibody, Lama4 antibody

Background: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, however, the exact function of laminin, alpha 4 is not known. Tissue-specific utilization of alternative polyA-signal has been described in literature.
Alias Symbols: DKFZp686D23145, LAMA3, LAMA4*-1
Protein Interaction Partner: RTN4, APC, LRIF1, COPS6, MED31, BRD7, ZHX1, ATF7IP, UBR1, UNC119, TP53, PTN, GAPDH, EEF1A1, TUBB2A,
Protein Size: 120

Molecular Weight: 10 kDa

Gene ID: 3910

NCBI Accession: NM_001105209, NP_001098679

Pathways: Brown Fat Cell Differentiation