ARAF antibody (Middle Region)
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- Target See all ARAF Antibodies
- ARAF (V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog (ARAF))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Pig, Sheep, Cow, Dog, Rabbit, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARAF antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- PRGSPSPASV SSGRKSPHSK SPAEQRERKS LADDKKKVKN LGYRDSGYYW
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
- Characteristics
- This is a rabbit polyclonal antibody against ARAF. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ARAF
- Top Product
- Discover our top product ARAF Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 606 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ARAF (V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog (ARAF))
- Alternative Name
- ARAF (ARAF Products)
- Synonyms
- zgc:92074 antibody, wu:fk45h07 antibody, ARAF antibody, a-raf antibody, araf antibody, araf1 antibody, pks2 antibody, rafa1 antibody, A-RAF antibody, ARAF1 antibody, PKS2 antibody, RAFA1 antibody, 1200013E08Rik antibody, A-Raf antibody, AW495444 antibody, Araf1 antibody, A-Raf proto-oncogene, serine/threonine kinase antibody, A-Raf proto-oncogene, serine/threonine kinase L homeolog antibody, A-Raf proto-oncogene, serine/threonine kinase S homeolog antibody, Araf proto-oncogene, serine/threonine kinase antibody, araf antibody, ARAF antibody, araf.L antibody, araf.S antibody, Araf antibody
- Background
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ARAF belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily. It contains 1 phorbol-ester/DAG-type zinc finger, 1 protein kinase domain, and 1 RBD (Ras-binding) domain. ARAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus.
Alias Symbols: A-RAF, ARAF1, PKS2, RAFA1
Protein Interaction Partner: AGTRAP, KRAS, CDC37, MAP2K1, GNA12, FKBP5, UBC, RNF2, FBXO6, YWHAB, HIPK4, YWHAE, RRAS2, BAD, TEKT4P2, WNK1, NELFCD, DIDO1, TESK1, MAP2K2, MLH1, HSP90AA1, E2F6, BRAF, TIRAP, IRF7, IRAK2, YWHAG, MYO18A, CHD6, YWHAZ, PBK, NUDT14, KLHL12, COPS3, TIMM44, ASS1
Protein Size: 606 - Molecular Weight
- 67 kDa
- Gene ID
- 369
- NCBI Accession
- NM_001654, NP_001645
- UniProt
- P10398
- Pathways
- MAPK Signaling, RTK Signaling, Hepatitis C
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