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PHLDA1 antibody (C-Term)

PHLDA1 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785898
  • Target See all PHLDA1 Antibodies
    PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1))
    Binding Specificity
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 38
    • 15
    • 14
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog
    Host
    • 35
    • 4
    Rabbit
    Clonality
    • 37
    • 2
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHLDA1 antibody is un-conjugated
    Application
    • 27
    • 22
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LAVKSTRQKQ QHLVQQQPPS QPQPQPQLQP QPQPQPQPQP QPQSQPQPQP
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PHLDA1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human PHLDA1
    Top Product
    Discover our top product PHLDA1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 401 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tsuda, Davis, Argani, Shukla, McGill, Nagai, Saito, Laé, Fisher, Ladanyi: "TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition." in: Cancer research, Vol. 67, Issue 3, pp. 919-29, (2007) (PubMed).

  • Target
    PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1))
    Alternative Name
    PHLDA1 (PHLDA1 Products)
    Synonyms
    DT1P1B11 antibody, PHRIP antibody, TDAG51 antibody, Tdag antibody, pleckstrin homology like domain family A member 1 antibody, pleckstrin homology like domain, family A, member 1 antibody, pleckstrin homology-like domain, family A, member 1 antibody, pleckstrin homology-like domain, family A, member 1 L homeolog antibody, PHLDA1 antibody, Phlda1 antibody, phlda1.L antibody
    Background
    PHLDA1 is an evolutionarily conserved proline-histidine rich nuclear protein. It may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.
    Alias Symbols: DT1P1B11, MGC131738, PHRIP, TDAG51
    Protein Interaction Partner: UBC, SUMO1, MDFI, EGFR, APP, DNAJB1, HSPB1, HSPA4, ELAVL1, KRTAP4-12, RPL14, PLSCR1, HSPA4L, EIF3D, PABPC4,
    Protein Size: 401
    Molecular Weight
    45 kDa
    Gene ID
    22822
    NCBI Accession
    NM_007350, NP_031376
    UniProt
    Q8WV24
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