GNAO1 antibody (Middle Region)
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- Target See all GNAO1 Antibodies
- GNAO1 (Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1))
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Binding Specificity
- Middle Region
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Reactivity
- Mouse, Human, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig, Sheep, Zebrafish (Danio rerio), Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GNAO1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- CDVVSRMEDT EPFSAELLSA MMRLWGDSGI QECFNRSREY QLNDSAKYYL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against GNAO1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GNAO1
- Top Product
- Discover our top product GNAO1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 354 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Identification of plasma biomarker candidates in glioblastoma using an antibody-array-based proteomic approach." in: Radiology and oncology, Vol. 48, Issue 3, pp. 257-66, (2014) (PubMed).
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Identification of plasma biomarker candidates in glioblastoma using an antibody-array-based proteomic approach." in: Radiology and oncology, Vol. 48, Issue 3, pp. 257-66, (2014) (PubMed).
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- Target
- GNAO1 (Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1))
- Alternative Name
- GNAO1 (GNAO1 Products)
- Synonyms
- G-ALPHA-o antibody, GNAO antibody, AW050213 antibody, Galphao antibody, Gnao antibody, alphaO antibody, gnao1 antibody, wu:fq26h05 antibody, zgc:73315 antibody, RATBPGTPC antibody, XGalpha01 antibody, gnao1-A antibody, zgc:73153 antibody, G protein subunit alpha o1 antibody, guanine nucleotide binding protein, alpha O antibody, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a antibody, G protein subunit alpha o1 L homeolog antibody, Guanine nucleotide-binding protein G(o) subunit alpha antibody, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b antibody, GNAO1 antibody, Gnao1 antibody, gnao1a antibody, gnao1.L antibody, goa-1 antibody, gnao1b antibody
- Background
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Activated Goalpha interacted directly with PLZF, and enhanced its function as a transcriptional and cell growth suppressor. Goalpha might play a role in mediating extracellular signal-regulated kinase activation by G protein-coupled receptors in the brain.
Alias Symbols: DKFZp686O0962, G-ALPHA-o, GNAO
Protein Interaction Partner: UBC, ADRA2A, BAG3, Htt, RGS9, GABBR1, Haus4, RGS1, RIC8A, DCTN2, KLHL3, SCN8A, PDE6G, CRHR1, GPSM2, HRH4, NGB, S1PR5, RGS19, GRM6, FFAR2, TSHR, RGS5, RGS10, RGS7, RGS4, RGS16, RGS14, PTPRU, CCR5, NUCB1, PDE6H, CACNA1B, OPRM1, OPRD1, GNAO1, GNAI1, ADRA2C,
Protein Size: 354 - Molecular Weight
- 40 kDa
- Gene ID
- 2775
- NCBI Accession
- NM_138736, NP_620073
- UniProt
- B3KP89
- Pathways
- G-protein mediated Events
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