NPPC antibody (C-Term)

Catalog No. ABIN2787325

Product Details anti-NPPC Antibody

Target: NPPC (Natriuretic Peptide Type C (NPPC))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Goat, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPPC antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LLRDLRVDTK SRAAWARLLH EHPNARKYKG GNKKGLSKGC FGLKLDRIGS

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against Nppc. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Nppc

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 126 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPPC

Target: NPPC (Natriuretic Peptide Type C (NPPC))

Alternative Name: Nppc (NPPC Products)

Synonyms: CNPF antibody, CNPI antibody, CNPII antibody, Cnp1 antibody, CNP antibody, lbab antibody, CNP2 antibody, CNP3 antibody, cnp antibody, nppc antibody, 2',3'-cyclic nucleotide 3' phosphodiesterase antibody, natriuretic peptide type C antibody, natriuretic peptide C antibody, natriuretic peptide C S homeolog antibody, Cnp antibody, Nppc antibody, NPPC antibody, nppc.S antibody

Background: This gene encodes a member of the natriuretic peptide family. Natriuretic peptides are involved in the control of blood pressure, extracellular fluid volume and electrolyte homeostasis. The encoded protein also plays a role in sensory neuron bifurcation, and is a critical regulator of endochondral bone growth. The encoded protein is a ligand for the natriuretic peptide receptor B, and is synthesized as a preprohormone which is cleaved to produce a mature peptide. Mutations in this gene are associated with dwarfism resulting from impaired endochondral ossification.
Alias Symbols: CNP, MGC130574, lbab
Protein Interaction Partner: Npr2,
Protein Size: 126

Molecular Weight: 14 kDa

Gene ID: 18159

NCBI Accession: NM_010933, NP_035063

UniProt: Q61839