BPNT1 antibody (N-Term)
-
- Target See all BPNT1 Antibodies
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Pig, Dog, Guinea Pig, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This BPNT1 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- DRVTIQELTA PLLTTAQAKP GETQEEETNS GEEPFIETPR QDGVSRRFIP
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 91%
- Characteristics
- This is a rabbit polyclonal antibody against BPNT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human BPNT1
- Top Product
- Discover our top product BPNT1 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 261 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
- Alternative Name
- BPNT1 (BPNT1 Products)
- Synonyms
- BPNT1 antibody, PIP antibody, Sal3 antibody, BPntase antibody, 3'(2'), 5'-bisphosphate nucleotidase 1 antibody, bisphosphate 3'-nucleotidase 1 antibody, BPNT1 antibody, bpnt1.L antibody, Bpnt1 antibody
- Background
-
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Alias Symbols: PIP
Protein Interaction Partner: SUMO2, UBC, IQCB1,
Protein Size: 261 - Molecular Weight
- 29 kDa
- Gene ID
- 10380
- NCBI Accession
- NM_006085, NP_006076
- UniProt
- O95861
- Pathways
- Inositol Metabolic Process
-