NLRP5 antibody (N-Term)

Catalog No. ABIN2787916

The Rabbit Polyclonal anti-NLRP5 antibody (ABIN2787916) specifically detects NLRP5 in WB. The antibody is reactive with Human samples.

Quick Overview for NLRP5 antibody (N-Term) (ABIN2787916)

Target: NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NLRP5 Antibody

Binding Specificity: N-Term

Purpose: NLRP5 Antibody - N-terminal region

Sequence: LAWATSISIF ENMNLRTLSE KARDDMKRHS PEDPEATMTD QGPSKEKVPG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NLRP5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NLRP5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59021-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NLRP5

Target: NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))

Alternative Name: NLRP5

Background:

Background Information: The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis.

Gene Name: NLR family, pyrin domain containing 5

Alternative Symbols: MATER, NALP5, PAN11, PYPAF8, CLR19.8

Protein Name: NACHT, LRR and PYD domains-containing protein 5

Molecular Weight: 134kDa

Gene ID: 126206

NCBI Accession: NP_703148

UniProt: P59047

Pathways: Inflammasome