NLRP5 antibody (AA 157-256)

Catalog No. ABIN6144667

The Rabbit Polyclonal anti-NLRP5 antibody is suitable to detect NLRP5 in samples from Human. It has been validated for WB.

Quick Overview for NLRP5 antibody (AA 157-256) (ABIN6144667)

Target: NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NLRP5 Antibody

Binding Specificity: AA 157-256

Sequence: TMTDQGPSKE KVPGISQAVQ QDSATAAETK EQEISQAMEQ EGATAAETEE QEISQAMEQE GATAAETEEQ GHGGDTWDYK SHVMTKFAEE EDVRRSFENT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 157-256 of human NLRP5 (NP_703148.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NLRP5

Target: NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))

Alternative Name: NLRP5

Background: The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis.,NLRP5,CLR19.8,MATER,NALP5,PAN11,PYPAF8,Cell Biology & Developmental Biology,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,NLRP5

Molecular Weight: 134 kDa

Gene ID: 126206

UniProt: P59047

Pathways: Inflammasome