Calcitonin Receptor antibody (C-Term)

Catalog No. ABIN2788145

The Rabbit Polyclonal anti-Calcitonin Receptor antibody (ABIN2788145) specifically detects Calcitonin Receptor in WB. The antibody is reactive with Human, Cow, Dog and Guinea Pig samples.

Quick Overview for Calcitonin Receptor antibody (C-Term) (ABIN2788145)

Target: Calcitonin Receptor (CALCR)

Reactivity: Human, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcitonin Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Calcitonin Receptor Antibody

Binding Specificity: C-Term

Purpose: CALCR Antibody - C-terminal region

Sequence: NQRWGRRPSN RSARAAAAAA EAGDIPIYIC HQELRNEPAN NQGEESAEII

Predicted Reactivity: Cow: 77%, Dog: 79%, Guinea Pig: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CALCR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CALCR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59632-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Calcitonin Receptor

Target: Calcitonin Receptor (CALCR)

Alternative Name: CALCR

Background:

Background Information: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.

Gene Name: Calcitonin receptor

Alternative Symbols: CRT, CTR, CT-R, CTR1

Protein Name: Calcitonin receptor

Molecular Weight: 52kDa

Gene ID: 799

NCBI Accession: NP_001733

UniProt: P30988

Pathways: cAMP Metabolic Process