RASSF1 antibody (C-Term)
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- Target See all RASSF1 Antibodies
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat, Cow, Horse, Pig, Dog, Sheep, Zebrafish (Danio rerio), Guinea Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RASSF1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
- Characteristics
- This is a rabbit polyclonal antibody against RASSF1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human RASSF1
- Top Product
- Discover our top product RASSF1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 270 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- Alternative Name
- RASSF1 (RASSF1 Products)
- Synonyms
- RASSF1 antibody, zgc:92505 antibody, wu:fc17f02 antibody, zgc:112224 antibody, 123F2 antibody, NORE2A antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody, AA536941 antibody, AU044980 antibody, Rassf1A antibody, Rassf1B antibody, Rassf1C antibody, NPR2-like, GATOR1 complex subunit antibody, Ras association (RalGDS/AF-6) domain family 1 antibody, Ras association domain family member 1 antibody, putative rassf1 antibody, Ras association domain family member 1 L homeolog antibody, Ras association (RalGDS/AF-6) domain family member 1 antibody, NPRL2 antibody, rassf1 antibody, RASSF1 antibody, Smp_157340 antibody, rassf1.L antibody, Rassf1 antibody
- Background
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This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Alias Symbols: 123F2, NORE2A, RASSF1A, RDA32, REH3P21
Protein Interaction Partner: FBXW11, MDM2, DAXX, SUV39H2, KDM1A, SUV39H1, STK4, STK3, CDC20, SAV1, MAST2, HUWE1, LATS1, BTRC, UBC, ID1, GSK3B, C7orf25, C8orf33, KCNE3, CUL4A, DDB1, Rassf1, SKP2, AURKB, AURKA, SKP1, CUL1, NUDT10, MOAP1, CNKSR1, MAP1S, EXOSC8, RASSF5, TNFRSF10A, E4F1,
Protein Size: 270 - Molecular Weight
- 30 kDa
- Gene ID
- 11186
- NCBI Accession
- NM_170713, NP_733831
- UniProt
- Q9NS23
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