GADD45A antibody (C-Term)
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- Target See all GADD45A Antibodies
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
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Binding Specificity
- C-Term
- Reactivity
- Human, Cow, Horse, Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GADD45A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LRVSNPGRLA ELLLLETDAG PAASEGAEQP PDLHCVLVTN PHSSQWKDPA
- Predicted Reactivity
- Cow: 100%, Horse: 79%, Human: 100%, Pig: 93%, Rabbit: 86%
- Characteristics
- This is a rabbit polyclonal antibody against GADD45A. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human GADD45A
- Top Product
- Discover our top product GADD45A Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 165 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- Alternative Name
- GADD45A (GADD45A Products)
- Synonyms
- MGC53491 antibody, zgc:91795 antibody, gadd45a antibody, GADD45A antibody, ddit1 antibody, gadd45 antibody, GADD45 antibody, AA545191 antibody, Ddit1 antibody, DDIT1 antibody, Gadd45 antibody, growth arrest and DNA damage inducible alpha L homeolog antibody, growth arrest and DNA-damage-inducible, alpha, b antibody, growth arrest and DNA damage inducible alpha antibody, growth arrest and DNA damage-inducible protein 45 antibody, growth arrest and DNA-damage-inducible 45 alpha antibody, growth arrest and DNA-damage-inducible, alpha antibody, gadd45a.L antibody, gadd45ab antibody, GADD45A antibody, gadd45a antibody, GADD45 antibody, Gadd45a antibody
- Background
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GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of GADD45A gene is mediated by both p53-dependent and -independent mechanisms.
Alias Symbols: DDIT1, GADD45
Protein Interaction Partner: ING4, UBC, AURKA, STAT3, PCNA, MTOR, CDK1, APEX1, DCTN2, RPS7, MDM2, MAPK1, TIAL1, HNRNPA0, SH3GLB1, PTPRK, PSMC3, NUCB2, CDK11A, ASCC2, FAS, CCNB1, DNMT1, JMJD1C, UBR1, SYNE4, MIDN, IGSF21, FBN3, FAM83D, MICAL1, SPTBN4, NRBP1, DNAJC13, ZHX1, C14orf1, ADA
Protein Size: 165 - Molecular Weight
- 18 kDa
- Gene ID
- 1647
- NCBI Accession
- NM_001924, NP_001915
- UniProt
- P24522
- Pathways
- p53 Signaling, Cell Division Cycle
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