TTF1 antibody (Middle Region)
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- Target See all TTF1 Antibodies
- TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TTF1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KNSESTLFDS VEGDGAMMEE GVKSRPRQKK TQACLASKHV QEAPRLEPAN
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against TTF1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TTF1
- Top Product
- Discover our top product TTF1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 905 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))
- Alternative Name
- TTF1 (TTF1 Products)
- Synonyms
- TTF-1 antibody, TTF-I antibody, AV245725 antibody, RGD1565673 antibody, transcription termination factor 1 antibody, transcription termination factor, RNA polymerase I antibody, TTF1 antibody, Ttf1 antibody
- Background
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This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression.
Alias Symbols: TTF-1, TTF-I
Protein Interaction Partner: SMAD7, SMAD1, SIRT7, UBC, MDM2, CDKN2A, BAZ2A, KAT2B, PTRF, NFATC3,
Protein Size: 905 - Molecular Weight
- 103 kDa
- Gene ID
- 7270
- NCBI Accession
- NM_007344, NP_031370
- UniProt
- Q15361
- Pathways
- Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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